Bottle Overpressure in Liquid Supplements
Summary
A nutraceutical manufacturer faced unexpected bottle overpressure days after filling, raising safety and stability concerns that standard tests could not explain. This case study shows how non-destructive, time-resolved headspace analysis revealed the hidden gas and pressure dynamics inside sealed bottles over time, providing critical insight into what was happening beneath the surface. The findings point to how manufacturers can investigate delayed packaging failures without opening or destroying samples
Technology
The Gasporox sensors and instruments are built on more than 25 years of development and refinement in industrial laser-based gas measurement. The system uses Tunable Diode Laser Absorption Spectroscopy (TDLAS), a highly reliable and precise method for non-destructive headspace gas analysis.
Developed by Gasporox in collaboration with its technology partners, this laser sensor technology is widely used in demanding industries such as pharmaceuticals, petrochemicals, and energy.
Gasporox’s laser-based headspace analysis has been successfully deployed for over a decade in pharmaceutical manufacturing. It is integrated into fully automated inspection systems and benchtop instruments for 100% in-line and laboratory testing of vials, ampoules, and other parenteral packaging formats. The performance and robustness of the system have been validated through extensive real-world use.
